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Relative quantification (RQ) values in the examined groups of : (A) <t>P70S6K</t> , (B) TGF-β, (C) DNMT3b, and (D) Caspase-3 genes . Abbreviations: HCC, hepatocellular carcinoma; NPs, nanoparticles; RQ, relative quantification. ∗significant difference ( P < 0.05). ∗∗significant difference ( P < 0.01). ∗∗∗significant difference ( P < 0.001). ns, not significant.
Kda Ribosomal Protein S6 Kinase P70s6k, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Relative quantification (RQ) values in the examined groups of : (A) <t>P70S6K</t> , (B) TGF-β, (C) DNMT3b, and (D) Caspase-3 genes . Abbreviations: HCC, hepatocellular carcinoma; NPs, nanoparticles; RQ, relative quantification. ∗significant difference ( P < 0.05). ∗∗significant difference ( P < 0.01). ∗∗∗significant difference ( P < 0.001). ns, not significant.
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Relative quantification (RQ) values in the examined groups of : (A) <t>P70S6K</t> , (B) TGF-β, (C) DNMT3b, and (D) Caspase-3 genes . Abbreviations: HCC, hepatocellular carcinoma; NPs, nanoparticles; RQ, relative quantification. ∗significant difference ( P < 0.05). ∗∗significant difference ( P < 0.01). ∗∗∗significant difference ( P < 0.001). ns, not significant.
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Relative quantification (RQ) values in the examined groups of : (A) <t>P70S6K</t> , (B) TGF-β, (C) DNMT3b, and (D) Caspase-3 genes . Abbreviations: HCC, hepatocellular carcinoma; NPs, nanoparticles; RQ, relative quantification. ∗significant difference ( P < 0.05). ∗∗significant difference ( P < 0.01). ∗∗∗significant difference ( P < 0.001). ns, not significant.
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Relative quantification (RQ) values in the examined groups of : (A) <t>P70S6K</t> , (B) TGF-β, (C) DNMT3b, and (D) Caspase-3 genes . Abbreviations: HCC, hepatocellular carcinoma; NPs, nanoparticles; RQ, relative quantification. ∗significant difference ( P < 0.05). ∗∗significant difference ( P < 0.01). ∗∗∗significant difference ( P < 0.001). ns, not significant.
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Relative quantification (RQ) values in the examined groups of : (A) <t>P70S6K</t> , (B) TGF-β, (C) DNMT3b, and (D) Caspase-3 genes . Abbreviations: HCC, hepatocellular carcinoma; NPs, nanoparticles; RQ, relative quantification. ∗significant difference ( P < 0.05). ∗∗significant difference ( P < 0.01). ∗∗∗significant difference ( P < 0.001). ns, not significant.
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Relative quantification (RQ) values in the examined groups of : (A) <t>P70S6K</t> , (B) TGF-β, (C) DNMT3b, and (D) Caspase-3 genes . Abbreviations: HCC, hepatocellular carcinoma; NPs, nanoparticles; RQ, relative quantification. ∗significant difference ( P < 0.05). ∗∗significant difference ( P < 0.01). ∗∗∗significant difference ( P < 0.001). ns, not significant.
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Relative quantification (RQ) values in the examined groups of : (A) P70S6K , (B) TGF-β, (C) DNMT3b, and (D) Caspase-3 genes . Abbreviations: HCC, hepatocellular carcinoma; NPs, nanoparticles; RQ, relative quantification. ∗significant difference ( P < 0.05). ∗∗significant difference ( P < 0.01). ∗∗∗significant difference ( P < 0.001). ns, not significant.

Journal: Liver Research

Article Title: Therapeutic potential of miRNA-26a-encapsulated nanoparticles against hepatocellular carcinoma in a murine model

doi: 10.1016/j.livres.2025.10.002

Figure Lengend Snippet: Relative quantification (RQ) values in the examined groups of : (A) P70S6K , (B) TGF-β, (C) DNMT3b, and (D) Caspase-3 genes . Abbreviations: HCC, hepatocellular carcinoma; NPs, nanoparticles; RQ, relative quantification. ∗significant difference ( P < 0.05). ∗∗significant difference ( P < 0.01). ∗∗∗significant difference ( P < 0.001). ns, not significant.

Article Snippet: The expression of 70 kDa ribosomal protein S6 kinase (p70S6K), transforming growth factor beta (TGF-β), DNA methyltransferase 3 beta (DNMT3b), and Caspase-3 genes was analyzed utilizing the TaqMan gene expression master mix (Thermo Fisher Scientific, Waltham, MA, USA) in accordance with the manufacturer’s instructions.

Techniques: Quantitative Proteomics